IGF-1, IGFBP-1, and IGFBP-3 polymorphisms predict circulating IGF levels but not breast cancer risk: findings from the Breast and Prostate Cancer Cohort Consortium (BPC3).

IGF-1 has been shown to promote proliferation of normal epithelial breast cells, and the IGF pathway has also been linked to mammary carcinogenesis in animal models.We comprehensively examined the association between common genetic variation in the IGF1, IGFBP1, and IGFBP3 genes in relation to circulating IGF-I and IGFBP-3 levels and breast cancer

read more

Postpartum spontaneous vulvar hematoma as a cause of maternal near miss: a case report and review of the literature

Abstract Background Postpartum spontaneous vulvar hematoma is a rare complication of childbirth that can potentially cause maternal death if not managed Gun Care properly and in a timely manner.Case summary We present the case of maternal near miss secondary to postpartum hemorrhage secondary to vulvar hematoma after home delivery in a 28-year-old

read more

Diagnostic ability of confocal scanning ophthalmoscope for the detection of concurrent retinal disease in eyes with asteroid hyalosis.

PurposeTo compare the diagnostic capacity of a color fundus camera (CFC), ultra-wide-field bicolor confocal scanning laser ophthalmoscope (BC-cSLO; OPTOS), and true-color confocal scanning ophthalmoscope (TC-cSO; EIDON) in detecting coexisting retinal diseases in eyes with asteroid hyalosis (AH).MethodsThe medical Dong Quai records of consecutive p

read more